Bovine Research Models

Bovine Viral Diarrhea Virus Type 1 & 2 Challenge Model

 Published Work:

Zimmerman, A.D., Boots, R.E., Valli, J.L., Chase, C.L. “Evaluation of protection against virulent bovine viral diarrhea virus type 2 in calves that had maternal antibodies and were vaccinated with a modified-live vaccine.” JAVMA, 228,11 (2006). 

 Zimmerman, A.D., Boots, R.E., Schnackel, J.A., Chase, C.L. “Efficacy of a modified-live virus vaccine administered to calves with maternal antibodies and challenged seven months later with a virulent bovine viral diarrhea type 2 virus.” The Bovine Practitioner, 43,1 (2009)

Bovine Viral Diarrhea Virus Fetal Protection Model Bovine Viral Diarrhea Virus Type 1 & 2 Challenge Model

Published Work:

Fairbanks, K.K., Rinehart, C.L., Ohnesorge, C., Loughin, M.M., Chase, C.L. “Evaluation of fetal protection against experimental infection with type 1 and typ 2 bovine viral diarrhea virus after vaccination of the dam with a bivalent modified-live virus vaccine.” JAVMA, 225,12 (2004)

Bovine Respiratory Syncytial Virus Challenge Model

Bovine Herpesvirus 1 Challenge Model

Published Work:

Kris Fogarty Fairbanks MS, Joe Cambell, and Christopher C. L. Chase, DVM, PhD, DACVM. “Rapid onset of protection against infectious bovine rhinotracheitis with a modified-live virus multivalent vaccine.” Veterinary Therapeutics, 5, 1 (2004).

Bovine Herpesvirus 1 Fetal Protection Challenge Model

Published Work:

Alicia D. Zimmerman, DVM, Robin E. Buterbaugh, MS, John M. Herbert BS, Jamie M. Hass, Nicole E. Frank, MS, Louis G. Luempert III. PhD, and Christopher C. L. Chase, DVM, PhD, DACVM. “Efficacy of bovine herpesvirus-1 inactivated vaccine against aborting and stillbirth in pregnant heifers.” JAVMA, 231, 9 (2007).

Bovine Coronavirus and Bovine Rotavirus Challenge Model

Bovine Leptospirosis Challenge

Pending Publications

Field Safety Nutrition Models 

• Feed and Weigh 
• Performance